Clostridium difficile (C.Diff) infection
Patient Information Leaflet
What is Clostridium difficile (C. diff)?
- Clostridium difficile (C. diff) is a type of bacteria that can cause diarrhoea.
- It often affects people who have been taking antibiotics.
- It can usually be treated with a different type of antibiotic.
How do you know if you have a C. diff infection?
Common symptoms of a C. diff infection include:
- diarrhoea
- a high temperature
- loss of appetite
- feeling sick
- a stomach-ache
How you get a C. diff infection?
- The C. diff bacteria usually lives harmlessly in your bowel along with lots of other types of bacteria.
- Sometimes when you take antibiotics, the balance of bacteria in your bowel can change, causing an infection.
- When someone has a C. diff infection, it can spread to other people very easily if the bacteria found in the person's poo gets onto objects and surfaces.
Who is at risk?
You're more likely to get a C. diff infection if:
- you are over 65 years
- you are taking, or have recently taken, antibiotics
- you are staying in hospital or a care home for a long time
- you have a weakened immune system - for example, from having a long-term condition like diabetes or kidney failure, or treatment like chemotherapy
- you are taking a proton pump inhibitor (PPI), such as omeprazole, or other medicines that reduce stomach acid
- you have had a C. diff infection in the past.
How to prevent spreading a C. diff infection
- The C. diff infections can spread very easily.
- There are some things you can do to reduce the risk of passing it on to others.
Do
- stay at home until at least 48 hours after your diarrhoea stops
- wash your hands regularly using soap and water
- clean the toilet and area around it with disinfectant after each use
- wash clothes and sheets with poo on separately from other washing at the highest possible temperature.
Don't
- do not share towels and flannels
- do not take medicine to stop diarrhoea like loperamide because it can prevent the infection being cleared from your body.
It's important to get medical advice if you:
- have diarrhoea and you are taking, or have recently taken, antibiotics
- you have bloody diarrhoea or bleeding from the bottom
- you have diarrhoea for more than 7 days.
- you can call 111 or get help from 111 online: https://111.nhs.uk/
Any further questions?
- If you have any further questions, please feel free to contact the Infection Control team, on 020 7288 3679, or you can ask the department manager to contact us.
- Additional information can be found on:
- NHS Health A to Z https://www.nhs.uk/conditions/c-difficile/
- NHS Choices: www.nhs.uk/
The information in this leaflet has been sourced from https://www.nhs.uk/conditions/c-dificile/
Published:
22 Feb 2024
Review:
22 Feb 2026
Reference:
GEN/NPE/IPC/C.diff/03

