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Clostridium difficile (C.Diff) infection

Patient Information Leaflet

What is Clostridium difficile (C. diff)?

  • Clostridium difficile (C. diff) is a type of bacteria that can cause diarrhoea.
  • It often affects people who have been taking antibiotics.
  • It can usually be treated with a different type of antibiotic.

How do you know if you have a C. diff infection?

  • Common symptoms of a C. diff infection include:

    • diarrhoea
    • a high temperature
    • loss of appetite
    • feeling sick
    • a stomach-ache

How you get a C. diff infection?

  • The C. diff bacteria usually lives harmlessly in your bowel along with lots of other types of bacteria.
  • Sometimes when you take antibiotics, the balance of bacteria in your bowel can change, causing an infection.
  • When someone has a C. diff infection, it can spread to other people very easily if the bacteria found in the person's poo gets onto objects and surfaces.

Who is at risk?

  • You're more likely to get a C. diff infection if:

    • you are over 65 years
    • you are taking, or have recently taken, antibiotics
    • you are staying in hospital or a care home for a long time
    • you have a weakened immune system - for example, from having a long-term condition like diabetes or kidney failure, or treatment like chemotherapy
    • you are taking a proton pump inhibitor (PPI), such as omeprazole, or other medicines that reduce stomach acid
    • you have had a C. diff infection in the past.

How to prevent spreading a C. diff infection

  • The C. diff infections can spread very easily.
  • There are some things you can do to reduce the risk of passing it on to others.

Do

  • stay at home until at least 48 hours after your diarrhoea stops
  • wash your hands regularly using soap and water
  • clean the toilet and area around it with disinfectant after each use
  • wash clothes and sheets with poo on separately from other washing at the highest possible temperature.

Don't

  • do not share towels and flannels
  • do not take medicine to stop diarrhoea like loperamide because it can prevent the infection being cleared from your body.

It's important to get medical advice if you:

  • have diarrhoea and you are taking, or have recently taken, antibiotics
  • you have bloody diarrhoea or bleeding from the bottom
  • you have diarrhoea for more than 7 days.
  • you can call 111 or get help from 111 online: https://111.nhs.uk/

Any further questions?

  • If you have any further questions, please feel free to contact the Infection Control team, on 020 7288 3679, or you can ask the department manager to contact us.
  • Additional information can be found on:

The information in this leaflet has been sourced from https://www.nhs.uk/conditions/c-dificile/

Published:
22 Feb 2024
Review:
22 Feb 2026
Reference:
GEN/NPE/IPC/C.diff/03