Research

We encourage all our patients to participate in clinical trials and research projects.

Our ongoing randomised clinical trials [Recruiting]

 - TARGIT - B: An international randomised controlled trial to compare targeted intra-operative radiotherapy boost with conventional external beam radiotherapy boost after lumpectomy for breast cancer in women with a high risk of local recurrence. Link: TARGIT-B trial

-  SUPREMO: Selective use of postmastectomy radiotherapy after mastectomy. Link: SUPREMO trial

- POETIC: A trial of a short course of hormone therapy before and after surgery for early breast cancer. Link: POETIC trial 

 - PERSEPHONE: A trial comparing 6 months and 12 months of trastuzumab (Herceptin) for early breast cancer. Link: PERSSEPHONE trial

Our research projects: you are most welcome to participate

- Motivated interview techniques to reduce chemotherapy fatigue: The use of Motivational Interviewing to elicit health behaviour changes in women post treatment as part of the survivorship programme.The initial pilot study will focus on the symptom fatigue associated with the treatment chemotherapy and how exercise can improve long term outcomes.

 - Online patient satisfaction survey: We encourage all our patients attending the breast unit to participate in improving breast services by registering their feedback and their say here.

Our randomised clinical trials [Stopped recruiting]

 - TARGIT-A: A phase III multicentre randomised trial comparing single dose targeted intraoperative radiotherapy (TARGIT) with 3-6 weeks of conventional whole breast external beam radiotherapy after lumpectomy for early breast cancer in women who are 45 years of age and older. Link: TARGIT-A trial

 - REACT: A phase III multicentre double blind randomised trial of celecoxib versus placebo in primary breast cancer patients. Link: REACT

 - IBIS II: Prevention: IBIS-II Prevention will see if a breast cancer treatment called anastrozole can help prevent breast cancer in women at high risk of the disease. Link: IBIS-II